Cell-permeable transgelin-2 as a potent therapeutic for dendritic cell-based cancer immunotherapy, Journal of Hematology & Oncology

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• • This schematic cell contains the major structures found in migrating cells A: in lamellipodia, branched actin filaments are generated at the plasma membrane by the signal responsive WASP-Arp2/3 machinery and maintained in fast treadmilling by a set of regulatory proteins. B: during cell migration, cells extend fingerlike protrusions called filopodia beyond the leading edge of protruding lamellipodia to sense the environment.

• Transgelin-2: a double-edged sword in immunity and cancer metastasis Frontiers in Cell and Developmental Biology, section Cell Growth and division

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• • This schematic cell contains the major structures found in migrating cells A: in lamellipodia, branched actin filaments are generated at the plasma membrane by the signal responsive WASP-Arp2/3 machinery and maintained in fast treadmilling by a set of regulatory proteins. B: during cell migration, cells extend fingerlike protrusions called filopodia beyond the leading edge of protruding lamellipodia to sense the environment.

• Microvilli_T_Cell

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• • Microvilli shedding induces T cell clonal expansion.

• Transgelin-2: a double-edged sword in immunity and cancer metastasis, Frontiers in Cell and Developmental Biology

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• • Schematic illustration of action of cell permeable TAGLN2 in tumor regulation.

• Inside blood vessel

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• • Inside blood vessel with red blood cells and white blood cells.

Inside blood vessel

• Inside blood vessel with red blood cells and white blood cells.

Lung imaging

• Visualization of cell-cell interaction in lung via intravital imaging

Lymphnode

• Anatomy & Physiology of Lymph Nodes

What happens when you have an inflammation?

• DCs patrol and arrest, and T cells patrol, cluster and arrest in lymphatic capillaries in mouse ear skin.

Brain neuron hippocampus

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• • Storing Memories in Your Synapses

Cell Organelles

• The Organs of the Cell

Butterfly on a flower

• Plat E Cell viewed under a microscope

Spleen

• Anatomy & Physiology of spleen

How cells become cancerous?

• Cell transformation is a process in which the addition of certain malignant characteristics in the cell due to alteration in genetic material induced by chemicals, carcinogens, radiations, viruses.

T cells look like jellyfish

• The migrating T cells with elongated filopodia-like uropod look like jellyfish.

Peeling(watercolor in sketchbook_272X393mm)

• 세포털갈이_ Cartoon of microvilli shedding in T cells

Transgelin-2 Sketch(watercolor in sketchbook_272X393mm)

• Schematic illustration of action of cell permeable TAGLN2 in tumor regulation.

Lymphnode(watercolor in sketchbook_272X393mm)

• Anatomy & Physiology of Lymph Nodes

Wound healing(watercolor in sketchbook_272X393mm)

• Injury or infection induce an inflammatory response, which is an array of cellular events that is a major component of the innate immune response. To illustrate, consider the events that would be expected to take place after a splinter of nail into your finger, the barrier function of the skin is breached, tissues are injured, and bacteria are introduced into the underlying tissues. Every single immune cell fights against infection to protect our body.

Spleen(watercolor in sketchbook_272X393mm)

• Anatomy & Physiology of spleen

Nsrp70

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• • Nsrp70