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School of Life Sciences

Silver Health Bio Research Center

  • Prof. : PARK Chul-Seung
  • Tel : 062) 715-2489
  • E-mail : cspark@gist.ac.kr

Introduction

Silver Health Bio Research Center established in 2015 is an affiliated organization of Integrated Aging Research Institute at GIST. At the center, nearly 90 full-time researchers, including 14 faculty members at GIST, conduct various aging-related research projects, focusing on molecular mechanisms of biological aging and pathophysiology of geriatric disorders, with multidisciplinary approaches. This way, we hope to solve problems and challenges related super aged society by developing fundamental technologies that can readily be applied for silver industry.

Research Purpose

The Silver Health Bio Research Center aims to develop social skills to cope with the aging and to develop original technology for the aging-related industry through comprehensive interdisciplinary research on the aging phenomenon of life. In addition, the systematic and specialized research capacity and the aging research group are being integrated to grow into a specialized research institute for the control of aging and geriatric diseases.

Research Purpose - No., Research Topics, Research Information
No. Research Topics Research Information
1 Basic research on aging
  • Aging mechanisms identified by the gene discovery and functional studies.
  • Aging mechanisms based on molecular- and cellular-level.
  • Development of aging index and aging control method and control study.
  • Basic research of aging-related diseases.
2 Basic research on geriatric diseases
  • Development of innovative source technologies for the control, prevention and treatment of geriatric diseases caused by aging.
  • Obtaining original technology such as development of the molecular target through basic research and intermediary research of geriatric diseases and securing therapeutic target.
3 Multi- and inter-disciplinary research on biological aging and related diseases
  • Development of fusion technology and product for diagnosis, prevention and control of aging and related diseases.
4 Establishment of animal models for geriatric disorders
  • Established disease model animal research center for research on aging and related diseases.
  • Establishment of support system for aging related research through development, acquisition and supply of animal model of geriatric disease.
  • The pursuit of a global hub of basic research on aging and related diseases.

Expectations and Prospect

The Silver Health Bio Research Center will identify various social problems caused by population aging through basic research on aging and geriatric diseases, and will identify various solutions for maintaining national competitiveness. We will provide the basis for the world best research center for aging and geriatric disease through the selection and intensive support policy for excellence in the previous year. In addition, through practical joint research between basic research on aging and applied research, we will build a practical technology development system for solving social problems due to the entry of aging society. Therefore, it is expected to create a new paradigm of the aging research industry utilizing original technology and convergence technology for degenerative disease and to open up a new market.

EResearch Achievements

  • Matrix crosslinking-mediated mechanotransduction promotes post-traumatic osteoarthritis, P NATL ACAD SCI USA (2015).
  • Regulation of the Catabolic Cascade in Osteoarthritis by the Zinc-ZIP8-MTF1 Axism, Journal of Cell Biology (2014).
  • Abatacept alleviates severe autoimmune symptoms in a patient carrying a de novo variant in CTLA-4, Journal of Allergy and Clinical Immunology (2015).
  • SNAREs support atlastin-mediated homotypic ER fusion in Saccharomyces cerevisiae, Journal of Cell Biology (2015).
  • splicing inhibition of U2AF65 leads to alternative exon skipping, P NATL ACAD SCI USA (2015).
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